Insulin Detemir (Large Doses)

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to jrufo@ismp.org

2 posts / 0 new
Last post
Zachary Allen W...
Zachary Allen Wallace's picture
Offline
Last seen: 14 hours 58 min ago
Joined: 05/11/2018 - 10:24
Insulin Detemir (Large Doses)

Hi all,

Our current inpatient practice for insulin detemir (U-100) is unit-dose preparation by pharmacy using vials and 1 mL insulin syringes.

Doses ~greater than 75 units can cause the syringe to become unstable and plunger/stopper to possibly fall out (stopper is close to the end)

Alternative solutions come with pros and cons; curious to see what other facilities are doing for these larger doses.

Examples:
1. Using pens?
2. Concentrated insulin vial (e.g., U-500 with U-500 syringe)?
3. Drawing up in a 3 mL luer-lock syringe with additional warning labeling (e.g., "For Subcutaneous Use")?
4. Multiple 1 mL syringes (split doses)?

Thank you,

Zach