Hello,

Have any hospitals removed combination opioid-acetaminophen products from formulary and have any pearls for how to minimize risk in transitions of care? Our P&T committee is broadly supportive that these products increase risk of cumulative acetaminophen toxicity and don't allow for optimal pain management and it is relatively straightforward to use alternatives for new starts inpatient. The major barrier/pushback is with patients taking these products at home and minimizing medication reconciliation errors on admission and discharge.

Appreciate any insights or lessons learned if anyone has done this.

Thanks!
Lauren Gashlin
University of Rochester