Dilution of IV phenytoin doses

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to jrufo@ismp.org. 

1 post / 0 new
Log in or register to post comments
Thu, 11/05/2020 - 11:16
#1
Amaris Fuentes
Amaris Fuentes's picture
Offline
Last seen: 4 months 3 weeks ago
Joined: 11/13/2018 - 10:40
Dilution of IV phenytoin doses

Good morning - we are currently reviewing our practices with phenytoin IV administration. We offer opportunities to order both as IV push and IVPB and would like to move away from IV push. We, however, are finding information regarding final dilution of phenytoin to be no less than 5mg/mL, which would mean dilution of a typical 100mg in only 20cc. I am, however, not finding information on what the implications of further dilution in 50 or 100mL would be. Appreciate if others can share their phenytoin IV practices and dilutions.

Top