Midazolam Dosing Units in EMR and Infusion Pumps for status epilepticus

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Wed, 03/20/2024 - 11:06

Rachael Moran Lu

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Joined: 01/22/2018 - 14:46

Midazolam Dosing Units in EMR and Infusion Pumps for status epilepticus

What units do you use for midazolam for status epilepticus in your EMR and infusion pumps

Currently, ASHP standardize for safety recommendations for midazolam dosing units is MG/HR

But dosing recommendations for midazolam for status epilepticus for continuous infusion are mg/kg/hr in guidelines and references

Thanks

After initial loading dose, begin continuous infusion at 0.05 to 2 mg/kg/hour and titrate to cessation of electrographic seizures/burst suppression. For breakthrough status epilepticus, administer bolus of 0.1 to 0.2 mg/kg every 3 to 5 minutes in addition to increasing infusion rate by 0.05 to 0.1 mg/kg/hour every 3 to 4 hours (Ref). Some experts use doses up to 3 mg/kg/hour (Ref).

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