When we have questions or suggestions about a drug-drug interaction severity level rating, we share this with First DataBank, the drug information vendor for our homegrown EHR. A pharmacist from FDB typically responds to our emails within 2 weeks. They don't often make a change based on our emails, but they at least acknowledge our concern and explain their rationale.
In contrast, the drug information vendor servicing our pharmacy platform, MediSpan, has not yet responded to the few drug-drug interaction rating queries we've sent.