Due to national backorder of Lorazepam 2mg/ml vials, we were considering drawing up Lorazepam injection into BD 1ml syringes for IV administration. Does anyone have any info on stability when transferred from Multidose 30ml vial into 1ml labeled syringes by Pharmacy in the isolators?

Hello all,

We usually try to find good stability indicating studies (like stability indicating HPLC studies) to extend our compounded preparations (still within USP 797 BUD limit). For some reason we are unable to find anything other that stability studies according to measured PH and co2 levels...does anyone know if this is considered sufficient? if so, why? wouldn't this be only potency indicating, but stability indicating? I appreciate your help!

Thanks!