With EPIC now allowing for different drug-drug interaction settings for inpatient and outpatient settings we are evaluating the severity of drug interactions showing to our outpatient physicians and APPs.
1. Have any of you turned on additional severity drug drug interaction warnings for your outpatient prescribers knowing that they do not have the second barrier of pharmacist review prior to hitting the dispensing pharmacy?
2. What level of severity interactions show to your physicians and APPs? Does it differ for inpatient vs outpatient?

When we have questions or suggestions about a drug-drug interaction severity level rating, we share this with First DataBank, the drug information vendor for our homegrown EHR. A pharmacist from FDB typically responds to our emails within 2 weeks. They don't often make a change based on our emails, but they at least acknowledge our concern and explain their rationale.
In contrast, the drug information vendor servicing our pharmacy platform, MediSpan, has not yet responded to the few drug-drug interaction rating queries we've sent.