Alteplase shortage

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to

3 posts / 0 new
Last post
Amaris Fuentes
Amaris Fuentes's picture
Last seen: 3 weeks 18 hours ago
Joined: 11/13/2018 - 10:40
Alteplase shortage

Hi everyone -

We are planning for some changes in administration of alteplase given a shortage of 100mg vials. The manufacturer recommendations note to place into an empty bag but that is not a typical bedside process for us. Has anyone investigated other options? Or have plans for safeguards for the bedside transfer to bag?