AUC:MIC Vancomycin Dosing

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Matthew Hamrick
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Joined: 07/01/2021 - 10:48
AUC:MIC Vancomycin Dosing

My Hospital system recently implemented AUC:MIC dosing and monitoring for vancomycin. We are running into issues around RNs running vanco infusions over longer durations due to concerns for extravasation in certain patients. RNs are not always communicating the patients that are receiving longer than prescribed infusions and the peak blood draws are coming back elevated in some cases as a result. I was wondering if anyone else has been running into this issue and what strategies you have used to increase compliance/accuracy of trough and peak vanco levels after transitioning to AUC:MIC?

For reference, our hospital is using an in-house calculator rather than Bayesian software.

Thanks!