Dihydroergotamine

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Thu, 05/02/2024 - 11:03
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Meg Jennings
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Joined: 08/09/2023 - 15:44
Dihydroergotamine

For intermittent dosing of IV DHE for pediatric patients with migraines. Is there evidence to support dilution of the medication (stability). Have your team's extended the duration of administration beyond 2-3 minutes.

What evidence sources did you utilize for stability to dilute and extend the duration?

Lexicomp:
IV: Children ≥6 years and Adolescents: May be administered undiluted slowly over 2 to 3 minutes; or diluted and infused over 60 minutes (Ref). Test doses have been administered over 5 minutes

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