Enoxaparin Dispensing -- Small Doses

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to jrufo@ismp.org

5 posts / 0 new
Last post
Amanda Hurst
Amanda Hurst's picture
Offline
Last seen: 1 year 1 month ago
Joined: 04/22/2023 - 05:57
Enoxaparin Dispensing -- Small Doses

For enoxaparin preparation/dispensing for doses that are not commercially available in syringes:
1) Do you allow doses to be dispensed in insulin syringes?
2) Do you use a dilution for doses less than 10mg or less than 5mg?
3) What concentration do you make your dilution?

We currently allow using the 100 mg/mL product down to 5mg (then use a 20 mg/mL dilution) and do not use insulin syringes for any doses. However, we've anecdotally noticed that after switching away from using insulin syringes for doses 5-10 mg, there was great variability in the enoxaparin anti-Xa's.

Amanda Hurst
Sanford USD Medical Center
amanda.hurst@sanfordhealth.org