etoposide precipitation

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to jgold@ismp.org

1 post / 0 new
Lucy Chen
Lucy Chen's picture
Offline
Last seen: 2 months 1 week ago
Joined: 11/14/2019 - 23:28
etoposide precipitation

Hi everyone,

I have had some questions regarding etoposide precipitation when a peristaltic pump is used to infuse this drug. However, from what I can find in the literature the language is soft, i.e. "non-peristaltic pump preferred" or "peristaltic pump MAY increase drug precipitation".

I'm wondering if anyone has encountered this previously? If you use a peristaltic type pump institution wide, would you change to a different pump specifically for etoposide? Also helpful to know if you do use this pump type for etoposide with no issues.

Thanks very much in advance!