We are seeing an increase in ferric gluconate infusion reactions, resulting in some ED visits. I saw there was some discussion on this earlier. I wanted to see how everyone is administering and storing the ferrlecit. We use Hikma product and their manufacturer does not have refrigeration stability but based on Trissels and a published study on a different generic, we store in refrigeration for 7 days. We also have 250mg diluted in 250 mL and administered over one hour. Interestingly, we don't see the same anaphylaxis reactions in our inpatient doses, which are made on demand.
At your institution:
- do you dilute 250mg dose in 250 mL?
- How long do you infuse it over?
- How long do you store in room temp and in refrigerator?

Have you noticed any correlation in ferric gluconate reactions?