Heparin Infusion Monitoring Labs: Anti-Xa or aPPT

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Fri, 01/24/2025 - 21:16
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Joshua Matson
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Joined: 01/20/2025 - 18:20
Heparin Infusion Monitoring Labs: Anti-Xa or aPPT

Hello Everyone,
Currently the health system I am at uses 3 different therapeutic heparin infusion protocols across different hospitals with 2 protocols using aPTT monitoring and 1 using Anti-Xa monitoring with aPTT for patients on DOACs prior to admission and other indicated patients.
We are looking to standardize the protocols with using one primary monitoring system of either aPTT or anti-Xa (with aPTT for indicated patients) I was hoping to find out what is used at other practice sites and any literature/ details about how your site arrived at that decision. I’ve struggled to find literature highlighting clinical differences between the two monitoring systems.
Thank you for any information you can offer!

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