We have received reports from our cath/EP lab of patients not demonstrating the intended anticoagulant effect, a therapeutic ACT, from Hospira's Heparin 10,000 units/10 ml NDC 0409-2720-31, lot HA0269, exp 2/1/2025 following administration of typical bolus doses of this product. Alternative heparin product did result in intended effect. Case reviews are underway for identifiable contributing factors to heparin resistance.
This experience has been reported to FDA and manufacturer.
Anyone else identifying similar experience?