How does BUD compare to spike by time?

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Andre Tran
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Joined: 07/16/2021 - 14:59
How does BUD compare to spike by time?

Hi all,

There was some discussion in our pharmacy regarding BUD vs spike time. Let's say we have vancomycin 750 mg IVPB that was compounded with a BUD of 8/13 @0600. If a nurse were to hang it at 8/13 @0559 is that still okay knowing it is an hour infusion? Or

How do your facilities and USP interpret that? If the above scenario holds true, how does one interpret longer infusions (>4h)...nobody goes back and thinks "well it's past the BUD, but what time was it spiked?"

Any feedback is appreciated! Thanks.

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