Hydrocortisone Act-o-vial shortage

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to jrufo@ismp.org

1 post / 0 new
Margo Welsh
Margo Welsh's picture
Last seen: 12 months 1 day ago
Joined: 01/18/2022 - 10:44
Hydrocortisone Act-o-vial shortage

Good afternoon,

I was wondering if anyone has run into issues with the hydrocortisone act-o-vial shortage and utilizing the plain hydrocortisone vial with regard to the diluent used. The Pfizer package insert explicitly states to mix the plain vial with bacteriostatic water which has a preservative which then can not be used for neonates or intrathecal injections. I was wondering if anyone can share what they are doing during this shortage in the instance in which the act-o-vial in no longer available? Are you utilizing sterile water to dilute the plain vial? If so do you have any data to support? Thanks!