Morphine 0.4 mg/ml / recipe

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to

1 post / 0 new
Heidi Ault
Heidi Ault's picture
Last seen: 10 months 1 week ago
Joined: 11/16/2022 - 18:25
Morphine 0.4 mg/ml / recipe

Our institution currently makes a morphine PF 0.5 mg/ml from the parenteral product. However, I am used to using the 0.4 mg/ml concentration and would like to change to this (as well as being aligned with ASHP).

I realize there is an oral recipe diluting the commercially available Morphine 2 mg/ml oral solution. However, this product has sodium benzoate and sorbitol which is not recommended for use in pediatric and neonatal patients (if possible). Hence, why I am looking for a recipe for using the parenteral product.

Would anyone be able to share a recipe for Morphine 0.4 mg/ml using a parenteral product? Reference and BUD