Paclitaxel precipitation

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Mon, 12/30/2024 - 18:14
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Catherine Mueller
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Joined: 10/03/2022 - 13:30
Paclitaxel precipitation

Hi all,

Our organization has seen a pattern of paclitaxel precipitation specifically in the infusion set. This is despite using non-PVC bags, low sorb tubing, compatible CSTD (ChemoClave), and appropriate final concentrations within the PI recommended of 0.3 to 1.2 mg/mL.

Have other institutions been experiencing this and do you have any strategies to prevent precipitation during either the preparation or administration phase?

Thank you!

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