Our organization has recently been reviewing override data from our Alaris Guardrails and adjusting max/min for medications that are causing a high percentage of overrides. Propofol has emerged as an outlier for our organization in our ICU. Our current soft min is set at 50 mcg/kg/min but a large portion of our patients at certain hospitals are averaging 100-150 mcg/kg/min. I am wondering what other organizations have done with regard to limits on this medication since there are recommendations to try to maintain infusion rates below 67 mcg/kg/min to prevent PRIS. If you addressed practice, what strategies did you use to decrease your infusion rates?