Large language models in healthcare information research: making progress in an emerging field
The last 5 years have seen a rapid growth in research applying artificial intelligence or machine learning to improve the quality and safety of healthcare. This coincides with the release of web interfaces (such as ChatGPT from OpenAI and Copilot from Microsoft) that have enabled the general public (including health professionals and researchers) to easily access the latest generation of large language models (LLMs).
LLMs have fundamentally changed how machine learning is used across domains. Unlike previous generation systems that required careful data curation for specific tasks before training, modern LLMs work well with just a few examples or a simple problem description. This progress is mainly due to training on large volumes of web data that allows them to develop an ‘understanding’ of both language and general knowledge which they can then apply to a wide range of tasks.1
To fully comprehend the capabilities and associated...