Andexanet alfa administration

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Jeanie Misko
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Joined: 05/11/2020 - 23:44
Andexanet alfa administration

Hello,
I'm an Australian pharmacist. We have recently had andexanet alfa approved in Australia and I have several concerns about its safe administration, particularly as in Australia we don't have 24/7 onsite pharmacy services and nursing staff make up the majority of the intravenous medications.

Does your institution utilise an empty bag to prepare andexanet (and if so, which brand/plastic)?
Do you have both the bolus and infusion in the same bag?
What do you use for flushing please given there is lack of compatibility data for common fluids?

Many thanks for any information you can share, it is really appreciated.

All the best
Jeanie