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      Thu, 06/06/2024 - 14:07
                
    
    
        
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        sylvia castellano      
                    
  
      
                    
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          COMPOUNDING  ALTEPLASE SYRINGES        
      
      
        
  
    Hello Everyone,
     Years ago we use compound alteplase 1 mg syringes and freeze for 6 months pre USP 797. I realize the package insert states 8 hour stability. There are studies that support compounding stability and cyro storage of -30C  for 22 weeks. Any infor would be appreciated.