Fluorouracil Contamination

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to jgold@ismp.org

2 posts / 0 new
Last post
Laura Sosinski
Laura Sosinski's picture
Last seen: 6 days 22 hours ago
Joined: 10/05/2021 - 22:07
Fluorouracil Contamination

Hello All,

Lately, my institution has seen a lot of spore-like floaties in our Fluorouracil 5grams/100ml vials for injection. About 2 months ago I filled out a FDA Medwatch and called the manufacturer multiple times. The manufacturer finally got back to us and was of little help. Has anyone else noticed this? With the drug being on shortage it makes this really difficult, but we also do not want to use it as the package insert directly say so not use if there are floaties. Pictures of the issues are included (all of the pictures represent different vials). We have about 20 affected.

Attach files :