IM Promethazine in OB

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Tue, 01/28/2025 - 14:28
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Lindsey M Eick
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Joined: 07/12/2018 - 14:13
IM Promethazine in OB

Hi All
We still have IV promethazine on formulary (restricted to dispensing in IVPB bags from pharmacy) and our OB team is requesting to use IM promethazine for 'therapeutic rest' in some of our OB triage patients (patients not admitted, don't have IV access). They are citing the article below.

Obstetrical & Gynecological Survey
Therapeutic Rest as an Intervention in Early Labor: A Literature Review
September 2024 , Volume 79 ( 9 ), p 533 – 538

Does anyone allow this practice? If so how do you do this in a safe manor. The fear is that it will accidentally be given undiluted IV since that is how they are used to giving the medication. Has anyone else dealt with this issue and been able to NOT allow IM promethazine/use a different agent?

Thanks for your help!
Lindsey Eick
OHSU Medication Safety Supervisor

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