Hello - wondering if any institutions are giving lacosamide IV push at your institution? We have had some interest in this route to minimize delays in high risk/seizing patients. There is some literature that has made its way into tertiary resources, but unclear to me if folks are actually doing this (and any experiences to report). Thanks!
Davidson K, Newell J, Alsherbini K, et al. Safety and Efficiency of Intravenous Push Lacosamide Administration. Neurocrit Care 2018 (Epub ahead of print).
Husain A, Lee J, Kolls B, et al. Randomized trial of lacosamide versus fosphenytoin for nonconvulsive seizures. Ann Neurol 2018;83(6):1174-1185.
McLaughlin, K, Carabetta C, Hunt N, et al. Safety of Intravenous Push Lacosamide Compared With Intravenous Piggyback at a Tertiary Academic Medical Center. Annals of Pharmacotherapy. July 19, 2020
Hofler J, Unterberer I, Cobesberger J, et al. Intravenous lacosamide in status epilepticus and seizure clusters. Epilepsia 2011;52(10):e148-52.
Kellinghaus C, Berning S, Immisch I, et al. Intravenous lacosamide for treatment of status epilepticus. Acta Neurol Scan 2011;123:137-41.
Elsevier IV Push Administration of Drugs. 2020. https://www.elsevier.com/__data/assets/pdf_file/0010/1008955/IVP-Drug-Ad... Available at: Last accessed 10.26.2021