Magnesium Sulfate 50% for Eclamptic Seizures

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to

11 posts / 0 new
Last post
Stephen Rolfe
Stephen Rolfe's picture
Last seen: 1 year 3 months ago
Joined: 12/14/2019 - 15:50
Magnesium Sulfate 50% for Eclamptic Seizures

Good morning!

Our L&D group recently requested that we stock 10 or 20 mL vials of magnesium sulfate 50% on override in their ADC for the treatment of eclamptic seizures. This would be used for IM injection (5 gm in each buttock) if the patient does not have IV access. A few questions for the group:

1. Do you stock magnesium sulfate 50% vials in an ADC for the treatment eclamptic seizures? If yes, what vial size?

2. Do you have this medication on override?

3. If you stock in the ADC, do you have any safeguards in place to prevent inadvertent IV administration? Example – a custom clinical data category in Pyxis

Thanks in advance!

Stephen Rolfe, PharmD, BCCCP
Medication Safety and Compliance Officer
Maine Medical Center