Maximum Osmolarity for a Peripheral Parenteral Nutrition: Adult

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Megan Elizabeth...
Megan Elizabeth Fragale's picture
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Maximum Osmolarity for a Peripheral Parenteral Nutrition: Adult

Hello colleagues,

The ASPEN recommendation for maximum peripheral parenteral nutrition osmolarity (900 mOsm/L) is rated "weak." Literature supports a higher osmolarity (1200 mOsm/L) for neonates.

Do you allow for a higher osmolarity PPN in adults? If so, how do you justify it from a safety/risk for patient harm perspective?

Thank you,
Megan Fragale, PharmD, MS, BCPS
Medication Safety Officer
Skagit Regional Health