Perioperative Intravenous Lidocaine

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to jgold@ismp.org

3 posts / 0 new
Last post
Julie Botsford
Julie Botsford's picture
Offline
Last seen: 5 days 9 hours ago
Joined: 08/07/2009 - 10:54
Perioperative Intravenous Lidocaine

Is anyone utilizing intravenous lidocaine in the periop setting as part of a multimodal approach to reduce opioid need? Are you willing to share your experience?

If you considered this but are not doing it, why? A Cochrane review published in June 2018 concluded

" We are uncertain whether IV perioperative lidocaine, when compared to placebo or no treatment, has a beneficial impact on pain scores in the early postoperative phase, and on gastrointestinal recovery, postoperative nausea, and opioid consumption. The quality of evidence was limited due to inconsistency, imprecision, and study quality. Lidocaine probably has no clinically relevant effect on pain scores later than 24 hours. Few studies have systematically assessed the incidence of adverse effects. There is a lack of evidence about the effects of IV lidocaine compared with epidural anaesthesia in terms of the optimal dose and timing (including the duration) of the administration. We identified three ongoing studies, and 18 studies are awaiting classification; the results of the review may change when these studies are published and included in the review. "

Thanks so much!
Julie