Rabies immune globulin (HyperRAB) concentration change

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Kayla Cierniak
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Joined: 03/07/2017 - 09:35
Rabies immune globulin (HyperRAB) concentration change

We learned recently that there is a change in concentration for rabies immune globulin from Grifols (HyperRAB). The company told us that the product will now be 300 units per mL and not 150 units per mL as was the case with the previous formulation. Note that the 150 units/mL is still available for now but is being phased out.

Reason for the change to the higher concentration is to allow for less volume per injection into the area surrounding the wound. The dose is weight based (see package insert).

The previous product was also manufactured via a solvent/detergent process whereas the 300 unit/mL product is not.

Kayla

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