Has anyone had success in developing clinical decision support/alerts in Epic to mitigate the risk of respiratory depression, secondary to opioid stacking?

If so, would you be able to share how your clinical decisions support is built and any lessons learned along the way?
 
For additional context, we have had challenges managing the use of opioids in procedural areas when patients move between phases of care and patient care units. Often times there are numerous teams managing these patients requiring thorough handoffs, and communication regarding opioid administration and monitoring are missed.

It has been challenging to think about what logic could be used that would take into consideration patient-specific considerations/attributes and not cause alerts to fire excessively.

Curious if any sites have found success.

Thank you,

Chris Boreen, PharmD, MS
Director of Medication Safety and Drug Policy
Iowa Health Care