MSOS Discussion Board

Tenecteplase

Maria Cumpston's picture

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Hello -
We recently added tenecteplase to our formulary for use in MI. We also had a request to add tenecteplase for use in stroke. Has anyone else added tenecteplase to formulary for use in both indications? What safety measures have you put in place to help ensure that the correct dosing is used for each indication. We have hospitals within our system that are not 24/7 to think about as well.
Thanks -
Maria Cumpston, PharmD, CPPS
Medication Safety Officer
WVU Medicine

BUD of Pharmacy Bulk Packages

Karen Thompson's picture

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I am having a tough time wrapping my head around why we have to give opened Pharmacy Bulk Packages (PBP) a BUD of 4 hours, but we can continue using single dose vials for 6 hours (or 12 hours, if you follow the revised 2019 version of USP 797). Both products are preservative-free. Both products are only accessed within ISO Class 5 air (e.g., LAFW). In the case of calcium gluconate 10%, the ingredients of the SDV (10mL) and the Pharmacy Bulk Package (100mL) are IDENTICAL. Can someone please help me understand why we have to use shorter dating on a PBP in our cleanroom?

translation of sigs to other languages

Trecia Swanston's picture

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Our healthcare system uses EPIC. When translating prescription sigs from English to another language, if the sig typed does not exactly match the sig built for the translation, it will automatically revert the printed label instructions back to English. Example: “Take one tablet by mouth ONCE” will translate in Spanish. If I typed “Take one tablet by mouth ONCE before MRI” it reverts back to English if the “before MRI” is not built out.

Norepinephrine Drips Extended Stability Data

Marina Rabin's picture

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We are helping out our adult hospital, making some of their batches. One of the batches is making their Norepinephrine drips (8 mG/250 NS, 16mg / 250 NS and 32 mg/500 NS) The only stability they were able to provide us with is 24 hours RT. I tried to contact manufacturer to no avail. Can you please share your referenced stability data beyond 24 hours please?
Thank you much!!

Pyxis in COVID ICU

Rebecca Ellis's picture

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I’m wondering what other sites are doing re:Pyxis (or other ADC) in their COVID areas (ER, ICU, Medical unit)? Are you allowing them to be stored within COVID areas, or are they kept outside. The scenario I’m especially wondering about is a COVID unit where the whole ICU unit has been designated a closed negative pressure unit. Does anyone have, or are you preparing for, that type of scenario?

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